Guo-Qiang Bi received his B.S. in Physics from Peking University (1989), M.S. in Physics from New York University (1991) and Ph.D. in Biophysics from the University of California at Berkeley (1996). He was a postdoctoral fellow at the University of California at San Diego (1996-2000). He was appointed to be Assistant Professor at the Department of Neurobiology, University of Pittsburgh School of Medicine in 2000, where he was promoted to Associate Professor with tenure. In 2007, he established the Laboratory of Neurophysics at the University of Science and Technology of China, where he became a Xinchuang Professor and Changjiang Scholar. He has served as Chair of the Department of Neurobiology and Biophysics at USTC, and founding co-Director of the Center for Integrative Imaging at Hefei National Laboratory for Physical Sciences at the Microscale. His research focuses on understanding the structure and function of neuronal synapses and circuits. To this end, he and colleagues are also developing new microscopy tools for imaging at different scales.